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Brent crude, which on Tuesday rose to its highest level since a price plunge began in March, slipped 47 cents, or 1.1%, to $42.16 a barrel by 0814 GMT.
The benchmark crude has climbed from below $16 in April but remains a third lower than its level at the end of 2019.
A rising number of coronavirus cases in the United States, China, Latin America and India has unnerved investors.